[Risk factors for mortality in patients with chronic obstructive pulmonary disease].
Identifieur interne : 000165 ( Main/Exploration ); précédent : 000164; suivant : 000166[Risk factors for mortality in patients with chronic obstructive pulmonary disease].
Auteurs : Josep Montserrat-Capdevila [Espagne] ; Pere Godoy [Espagne] ; Josep Ramon Marsal [Espagne] ; Ferran Barbé-Illa [Espagne]Source :
- Atencion primaria [ 1578-1275 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen (MeSH), Broncho-pneumopathie chronique obstructive (mortalité), Espagne (épidémiologie), Facteurs de risque (MeSH), Femelle (MeSH), Humains (MeSH), Indice de gravité de la maladie (MeSH), Mâle (MeSH), Spirométrie (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Études rétrospectives (MeSH).
- MESH :
- mortalité : Broncho-pneumopathie chronique obstructive.
- épidémiologie : Espagne.
- Adulte d'âge moyen, Facteurs de risque, Femelle, Humains, Indice de gravité de la maladie, Mâle, Spirométrie, Sujet âgé, Sujet âgé de 80 ans ou plus, Études rétrospectives.
English descriptors
- KwdEn :
- MESH :
- epidemiology : Spain.
- mortality : Pulmonary Disease, Chronic Obstructive.
- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, Severity of Illness Index, Spirometry.
Abstract
OBJECTIVE
To identify risk factors of mortality in patients with chronic obstructive pulmonary disease (COPD).
DESIGN
A retrospective cohort study.
LOCATION
Primary care setting in Lleida, Spain.
PARTICIPANTS
2.501 patients older than 40 years with at least a spirometry in the 24 months prior to the beginning of the study were followed for 3 years.
MAIN MEASUREMENTS
The dependent variable was the overall mortality in the period 11/01/2010-10/31/2013; and the independents: spirometric parameters, severity (GOLD) and clinical variables. Their association with mortality was analyzed by calculating the adjusted odds ratio using a non-conditional logistic regression model.
RESULTS
The average age of 2.501 patients at the beginning of the study was 68.4 years (SD=11.6). 75.0% were males. 50.8% had a mild severity COPD, followed by moderate (35.3%), severe (9.4%) and very severe (4.4%). Mortality rate for the all period was 12.55%. The variables of the predictive model were: age, male sex, previous exacerbations, number of visits to primary care, comorbidity, smoking, severity of COPD (GOLD) and not receiving influenza vaccination, with an area under the ROC curve of 0.76.
CONCLUSIONS
This model, easy and quick to apply, would identify those patients at increased risk of mortality and who could benefit from preventive strategies to improve their survival.
DOI: 10.1016/j.aprim.2014.11.004
PubMed: 25778409
PubMed Central: PMC6983683
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Electronic address: jmontser@alumni.unav.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Biomèdica (IRB) Lleida, Lleida, España; Departament de Salut, Agència de Salut Pública de Catalunya, Lleida, España; CAP Mollerussa, Institut Català de la Salut (ICS), Mollerussa</wicri:regionArea><wicri:noRegion>Mollerussa</wicri:noRegion></affiliation></author><author><name sortKey="Godoy, Pere" sort="Godoy, Pere" uniqKey="Godoy P" first="Pere" last="Godoy">Pere Godoy</name><affiliation wicri:level="1"><nlm:affiliation>Institut de Recerca Biomèdica (IRB) Lleida, Lleida, España; Departament de Salut, Agència de Salut Pública de Catalunya, Lleida, España; Facultat de Medicina, Universitat de Lleida, Lleida, España.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Biomèdica (IRB) Lleida, Lleida, España; Departament de Salut, Agència de Salut Pública de Catalunya, Lleida, España; Facultat de Medicina, Universitat de Lleida, Lleida</wicri:regionArea><wicri:noRegion>Lleida</wicri:noRegion></affiliation></author><author><name sortKey="Marsal, Josep Ramon" sort="Marsal, Josep Ramon" uniqKey="Marsal J" first="Josep Ramon" last="Marsal">Josep Ramon Marsal</name><affiliation wicri:level="3"><nlm:affiliation>Unitat de Suport a la Recerca Lleida, Lleida, España; Institut Universitari d'Investigació en Atenció Primària (IDIAP) Jordi Gol, Universitat Autònoma de Barcelona, Barcelona, España; Unitat d'Epidemiologia del Servei de Cardiologia, Hospital Universitari Vall d'Hebron, Barcelona, España.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unitat de Suport a la Recerca Lleida, Lleida, España; Institut Universitari d'Investigació en Atenció Primària (IDIAP) Jordi Gol, Universitat Autònoma de Barcelona, Barcelona, España; Unitat d'Epidemiologia del Servei de Cardiologia, Hospital Universitari Vall d'Hebron, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Barbe Illa, Ferran" sort="Barbe Illa, Ferran" uniqKey="Barbe Illa F" first="Ferran" last="Barbé-Illa">Ferran Barbé-Illa</name><affiliation wicri:level="3"><nlm:affiliation>Institut de Recerca Biomèdica (IRB) Lleida, Lleida, España; Hospital Universitari Arnau de Vilanova, Lleida, España; Unitat d'Epidemiologia del Servei de Cardiologia, Hospital Universitari Vall d'Hebron, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, España.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Biomèdica (IRB) Lleida, Lleida, España; Hospital Universitari Arnau de Vilanova, Lleida, España; Unitat d'Epidemiologia del Servei de Cardiologia, Hospital Universitari Vall d'Hebron, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author></analytic><series><title level="j">Atencion primaria</title><idno type="eISSN">1578-1275</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Pulmonary Disease, Chronic Obstructive (mortality)</term><term>Retrospective Studies (MeSH)</term><term>Risk Factors (MeSH)</term><term>Severity of Illness Index (MeSH)</term><term>Spain (epidemiology)</term><term>Spirometry (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen (MeSH)</term><term>Broncho-pneumopathie chronique obstructive (mortalité)</term><term>Espagne (épidémiologie)</term><term>Facteurs de risque (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Indice de gravité de la maladie (MeSH)</term><term>Mâle (MeSH)</term><term>Spirométrie (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Études rétrospectives (MeSH)</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Spain</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Pulmonary Disease, Chronic Obstructive</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Broncho-pneumopathie chronique obstructive</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Risk Factors</term><term>Severity of Illness Index</term><term>Spirometry</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Indice de gravité de la maladie</term><term>Mâle</term><term>Spirométrie</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>To identify risk factors of mortality in patients with chronic obstructive pulmonary disease (COPD).</p></div><div type="abstract" xml:lang="en"><p><b>DESIGN</b></p><p>A retrospective cohort study.</p></div><div type="abstract" xml:lang="en"><p><b>LOCATION</b></p><p>Primary care setting in Lleida, Spain.</p></div><div type="abstract" xml:lang="en"><p><b>PARTICIPANTS</b></p><p>2.501 patients older than 40 years with at least a spirometry in the 24 months prior to the beginning of the study were followed for 3 years.</p></div><div type="abstract" xml:lang="en"><p><b>MAIN MEASUREMENTS</b></p><p>The dependent variable was the overall mortality in the period 11/01/2010-10/31/2013; and the independents: spirometric parameters, severity (GOLD) and clinical variables. Their association with mortality was analyzed by calculating the adjusted odds ratio using a non-conditional logistic regression model.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>The average age of 2.501 patients at the beginning of the study was 68.4 years (SD=11.6). 75.0% were males. 50.8% had a mild severity COPD, followed by moderate (35.3%), severe (9.4%) and very severe (4.4%). Mortality rate for the all period was 12.55%. The variables of the predictive model were: age, male sex, previous exacerbations, number of visits to primary care, comorbidity, smoking, severity of COPD (GOLD) and not receiving influenza vaccination, with an area under the ROC curve of 0.76.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>This model, easy and quick to apply, would identify those patients at increased risk of mortality and who could benefit from preventive strategies to improve their survival.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">25778409</PMID><DateCompleted><Year>2017</Year><Month>09</Month><Day>06</Day></DateCompleted><DateRevised><Year>2020</Year><Month>01</Month><Day>31</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1578-1275</ISSN><JournalIssue CitedMedium="Internet"><Volume>47</Volume><Issue>8</Issue><PubDate><Year>2015</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Atencion primaria</Title><ISOAbbreviation>Aten Primaria</ISOAbbreviation></Journal><ArticleTitle>[Risk factors for mortality in patients with chronic obstructive pulmonary disease].</ArticleTitle><Pagination><MedlinePgn>498-504</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.aprim.2014.11.004</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0212-6567(14)00392-8</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To identify risk factors of mortality in patients with chronic obstructive pulmonary disease (COPD).</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">A retrospective cohort study.</AbstractText><AbstractText Label="LOCATION" NlmCategory="METHODS">Primary care setting in Lleida, Spain.</AbstractText><AbstractText Label="PARTICIPANTS" NlmCategory="METHODS">2.501 patients older than 40 years with at least a spirometry in the 24 months prior to the beginning of the study were followed for 3 years.</AbstractText><AbstractText Label="MAIN MEASUREMENTS" NlmCategory="METHODS">The dependent variable was the overall mortality in the period 11/01/2010-10/31/2013; and the independents: spirometric parameters, severity (GOLD) and clinical variables. Their association with mortality was analyzed by calculating the adjusted odds ratio using a non-conditional logistic regression model.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The average age of 2.501 patients at the beginning of the study was 68.4 years (SD=11.6). 75.0% were males. 50.8% had a mild severity COPD, followed by moderate (35.3%), severe (9.4%) and very severe (4.4%). Mortality rate for the all period was 12.55%. The variables of the predictive model were: age, male sex, previous exacerbations, number of visits to primary care, comorbidity, smoking, severity of COPD (GOLD) and not receiving influenza vaccination, with an area under the ROC curve of 0.76.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This model, easy and quick to apply, would identify those patients at increased risk of mortality and who could benefit from preventive strategies to improve their survival.</AbstractText><CopyrightInformation>Copyright © 2014 Elsevier España, S.L.U. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Montserrat-Capdevila</LastName><ForeName>Josep</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Institut de Recerca Biomèdica (IRB) Lleida, Lleida, España; Departament de Salut, Agència de Salut Pública de Catalunya, Lleida, España; CAP Mollerussa, Institut Català de la Salut (ICS), Mollerussa, España. Electronic address: jmontser@alumni.unav.es.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Godoy</LastName><ForeName>Pere</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Institut de Recerca Biomèdica (IRB) Lleida, Lleida, España; Departament de Salut, Agència de Salut Pública de Catalunya, Lleida, España; Facultat de Medicina, Universitat de Lleida, Lleida, España.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marsal</LastName><ForeName>Josep Ramon</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Unitat de Suport a la Recerca Lleida, Lleida, España; Institut Universitari d'Investigació en Atenció Primària (IDIAP) Jordi Gol, Universitat Autònoma de Barcelona, Barcelona, España; Unitat d'Epidemiologia del Servei de Cardiologia, Hospital Universitari Vall d'Hebron, Barcelona, España.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barbé-Illa</LastName><ForeName>Ferran</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Institut de Recerca Biomèdica (IRB) Lleida, Lleida, España; Hospital Universitari Arnau de Vilanova, Lleida, España; Unitat d'Epidemiologia del Servei de Cardiologia, Hospital Universitari Vall d'Hebron, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, España.</Affiliation></AffiliationInfo></Author></AuthorList><Language>spa</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><VernacularTitle>Factores asociados a la mortalidad global en los pacientes diagnosticados de enfermedad pulmonar obstructiva crónica.</VernacularTitle><ArticleDate DateType="Electronic"><Year>2015</Year><Month>03</Month><Day>13</Day></ArticleDate></Article><MedlineJournalInfo><Country>Spain</Country><MedlineTA>Aten Primaria</MedlineTA><NlmUniqueID>9111075</NlmUniqueID><ISSNLinking>0212-6567</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D029424" MajorTopicYN="N">Pulmonary Disease, Chronic Obstructive</DescriptorName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012720" MajorTopicYN="N">Severity of Illness Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N">Spain</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013147" MajorTopicYN="N">Spirometry</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Chronic obstructive pulmonary disease</Keyword><Keyword MajorTopicYN="N">Enfermedad pulmonar obstructiva crónica</Keyword><Keyword MajorTopicYN="N">Factores de Riesgo</Keyword><Keyword MajorTopicYN="N">Mortalidad</Keyword><Keyword MajorTopicYN="N">Mortality</Keyword><Keyword MajorTopicYN="N">Risk 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Madrid</li></region><settlement><li>Barcelone</li><li>Madrid</li></settlement></list><tree><country name="Espagne"><noRegion><name sortKey="Montserrat Capdevila, Josep" sort="Montserrat Capdevila, Josep" uniqKey="Montserrat Capdevila J" first="Josep" last="Montserrat-Capdevila">Josep Montserrat-Capdevila</name></noRegion><name sortKey="Barbe Illa, Ferran" sort="Barbe Illa, Ferran" uniqKey="Barbe Illa F" first="Ferran" last="Barbé-Illa">Ferran Barbé-Illa</name><name sortKey="Godoy, Pere" sort="Godoy, Pere" uniqKey="Godoy P" first="Pere" last="Godoy">Pere Godoy</name><name sortKey="Marsal, Josep Ramon" sort="Marsal, Josep Ramon" uniqKey="Marsal J" first="Josep Ramon" last="Marsal">Josep Ramon Marsal</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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